Martin Christian Michel ICS Chair
Karl-Erik Andersson ICS Chair
16:30
#227 Mechanisms underlying purinergic P2X7 receptor antagonism in maintaining urothelial barrier function against acrolein-induced damage and cytotoxicity Best in Category Prize: Pharmacology
Presenter: Zhinoos Taidi
Taidi Z1, Liang C1, Mansfield K2, Moore K3, Liu L11.University of New South Wales, 2.University of Wollongong, 3.St.George hospital, University of New South Wales Basic Science, Painful Bladder Syndrome/Interstitial Cystitis (IC), Pharmacology, Cell Culture
16:37
#228 Extracellular ATP mediates P2X7R activation-dependent large pore-formation and interleukin-1β release in the mouse urinary bladder
Presenter: Muhammad Fahad
Fahad M1, Bashir S1, Ahsan H1, Noreen M21.University of Sargodha, 2.Tehsil Headquater Hospital Hazro Cell Culture, Molecular Biology, Pharmacology, Painful Bladder Syndrome/Interstitial Cystitis (IC), Basic Science
16:45
#229 Urinary ATP concentrations are related to detrusor pressure during voiding
Presenter: Ana Lopes
Silva-Ramos M1, Lopes A1, Silva D2, Silva I2, Correia-de-Sá P21.Department of Urology, Centro Hospitalar Universitário do Porto, 2.Laboratório de Farmacologia e Neurobiologia, Instituto de Ciências Biomédicas Abel Salazar Benign Prostatic Hyperplasia (BPH), Bladder Outlet Obstruction , Detrusor Hypocontractility, Male, Voiding Dysfunction
16:52
#230 Interactions between cholinergic and purinergic transmitter systems directly affect the ATP-evoked contractile response of the rat urinary bladder in vivo
Presenter: Johanna Stenqvist
Stenqvist J1, Winder M1, Carlsson T1, Aronsson P11.Department of Pharmacology, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg Basic Science, Pharmacology, Neuromodulation
17:00
#231 EVALUATION OF URINARY ADENOSINE TRI PHOSPHATE (ATP) AND NITRIC OXIDE (NO) LEVELS IN PATIENTS WITH UNDERACTIVE BLADDER
Presenter: R Anand Krishnan
ANAND KRISHNAN1, SUDHEER KUMAR1, DEEPY1, RAVIMOHAN S1, ARUP KUMAR11.POST GRADUTE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH ,CHANDIGARH Underactive Bladder, Prospective Study, Biochemistry , Urodynamics Techniques
17:07
#232 Effects of a new β3-adrenoceptor agonist vibegron on neurogenic bladder dysfunction and remodeling in mice with spinal cord injury
Presenter: Daisuke Gotoh
Gotoh D1, Shimizu N1, Wada N1, Kadekawa K1, Saito T1, Mizoguchi S1, Kurobe M1, Torimoto K2, Fujimoto K2, Yoshimura N11.University of Pittsburgh, 2.Nara Medical University Animal Study, Detrusor Overactivity, Pharmacology, Physiology, Spinal Cord Injury
17:15
#233 Inhibitory effects of CL316243, a beta 3-adrenoceptor agonist, on the myogenic activities and on the mechanosensitive afferent activities in the obstructed rat bladder
Presenter: Daiji Watanabe
Watanabe D1, Aizawa N1, Suzuki M2, Kume H2, Igawa Y11.Department of Continence Medicine, The University of Tokyo Graduated School of Medicine, Tokyo, Japan, 2.Department of Urology, The University of Tokyo Graduated School of Medicine, Tokyo, Japan Animal Study, Bladder Outlet Obstruction , Physiology
17:22
#234 Long-term administration of alpha-1 blocker reverses the micturition pattern in bladder outlet obstruction mice
Presenter: Takeya Kitta
Kitta T1, Kanno Y1, Hattori T2, Chiba H1, Hguchi M1, Ouchi M1, Takahashi Y1, Togo M1, Kitano T3, Yoshikawa S3, Shinohara N11.Hokkaido University, 2.Department of Medical Affairs, Asahi Kasei Pharma Corporation, 3.Laboratory for Pharmacology, Pharmaceuticals Research Center, Asahi Kasei Pharma Corporation Bladder Outlet Obstruction , Nocturia, Pharmacology
17:30
#235 Excitatory Effect of Acotiamide on Nerve Evoked Contractions of Rat and Human Bladder
Presenter: Pradeep Tyagi
Tyagi P1, Mizoguchi S1, Chermansky C1, Yoshimura N11.University of Pittsburgh Underactive Bladder, Detrusor Hypocontractility, Pharmacology, Benign Prostatic Hyperplasia (BPH)
17:37
#236 The pharmacological properties of TAS-303 and its effects on urethral pressure in rat experimental model of stress urinary incontinence
Presenter: Hiroya Mizutani
Mizutani H1, Sakakibara F1, Komuro M1, Hakozaki A1, Hosoi F1, Ikizawa K1, Utsugi T11.Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan Stress Urinary Incontinence, Basic Science, Pharmacology
17:45
#237 NADPH oxidase-driven superoxide generation in bladder urothelium – effect of Nox subtype deletion and the inflammatory mediators
Presenter: C Wu
Wu1, Roberts1, Amosah1, Sui2, Wu3, Archer1, Ruggieri41.University of Surrey, 2.Guy's and St. Thomas Hospitals NHS Trust, 3.University Hospital Coventry, 4.Temple University Basic Science, Pharmacology, Pathophysiology, Sensory Dysfunction, Molecular Biology
17:52
#238 Oxidative stress changes in the rat bladder induced by nicotine treatment
Presenter: Panagiota Tsounapi
Tsounapi P1, Honda M1, Teraoka S1, Kimura Y1, Zachariou A2, Dimitriadis F3, Hikita K1, Sofikitis N2, Saito M4, Takenaka A11.Division of Urology Tottori University Faculty of Medicine, 2.Department of Urology Ioannina University School of Medicine, 3.Department of Urology Aristotle University School of Medicine, 4.Department of Pharmacology, Kochi Medical School, Kochi University Basic Science, Biochemistry , Animal Study
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