During the study period, 545 patients were referred to our third referral centre with the main symptoms of ODS, 471 females (86.4%) and 74 males (13.6%). Based on results from last appointment, patients have been classified into two groups “improvement” and “no improvement”. Several predicting factors have been analysed to understand if we can stratify patients during their initial assessment.
Among demographic data, only age have reach statistical significance to predict improvement (median age is 51.6 in improvement group and 48.5 in the non-improvement, p=0.019). On the contrary, sex, previous proctological or pelvic floor surgery, hysterectomy, vaginal deliveries haven’t been reach statistical significance as predictors.
Regards questionnaires, we have divided ICIQ-B in Bowel pattern symptoms (BPS), Bowel continence symptoms (BCS) and Quality of life (QoL) and we have found that patients with baseline worse QoL has worse outcomes (13.41 improvement vs 15.07 no improvement, p=0.012). Initial ODS score hasn’t results significant (9.7 improvement vs 9.8 no improvement, p=0.75) as well as Bristol stool chart (2.7 improvement vs 2.5 no improvement, p=0.2).
In terms of pelvic floor tests, 403 (74.9%) had endoanal ultrasound and anorectal manometry, while 385 (70.6%) had defaecating proctography. None of the results from tests have resulted to be significant in predicting patients’ outcomes (results reported in table 1 and 2).
Regards interventions, 485 (89%) patient had conservative treatment, with a median number of sessions of 4.28 (range between 0-16) and a length of follow-up of 14.4 months (range 0-67.7), while 51 (9.4%) had surgery when conservative measures failed to achieve patients’ satisfactory improvements. Conservative measures include counselling and correct toilet position training, information leaflets, pelvic floor exercises, prokinetics (19.8%), laxatives (37.1%), medications to increase the stools consistency (6.2%), use of suppositories (71.7%) and selective us of low and high volume irrigation (41.8%). None of them has been result a predictors of success for conservative treatment. Surgical interventions were offered to 51 (9.4%) in total, (11.5% in the improvement group and 5.3% in the no improvement group, p=0.02). Length of follow-up has been 14.8 months (16.6 in the improvement and 14.5 in the no improvement group, p=0.002).