The overall prevalence of PNE among adolescents aged 12 to 18 years was 2.98% (191/6408), with prevalence rates of 4.67%, 4.09%, 3.67%, 2.97%, 2.27%, 1.65%, and 1.37% for each age. The prevalence gradually decreased with age. The prevalence was 3.70% in males and 2.26% in females, with a significant difference (P<0.05). The prevalence of BMI ≥ 25kg/m2 was 5.43%, and the prevalence of BMI<25kg/m2 was 2.72%, with a significant difference (P<0.001). The patients with frequent urination accounted for 9.13%, while those without frequent urination accounted for 2.72%, with a significant difference (P<0.001). There was a significant difference between 5.20% with urgency and 2.51% without urgency (P<0.001). There was a significant difference between 14.47% with urinary incontinence and 2.70% without urinary incontinence (P<0.001). The patients with RUTI accounted for 8.59%, while those without RUTI accounted for 2.75%, with a significant difference (P<0.001). There was a significant difference between 9.46% with a family history of enuresis and 2.52% without a family history of enuresis (P<0.001). The prevalence rate was 2.96% in urban areas and 2.99% in rural areas, with no significant difference (P=0.948). (Table1)Multivariate logistic regression analysis of statistically significant factors in Chi-square analysis showed that male, overweight, urgency to urinate, frequency of urination, urinary incontinence, RUTI, and family history of enuresis (OR=1.677, 1.842, 1.676, 1.919, 3.493, 2.535, 3.005, P<0.05). The scores of the self-esteem scale in PNE patients were lower than those in non PNE groups [28(25,32) vs 29(27,33),z=-3.097, P<0.05]; Compared with the non PNE group, the Pittsburgh sleep index in the PNE group was higher than that in the non PNE group [5(3,7) vs 4(2,6), z=-5.456, P<0.05]. (Table 2)